ISDIN

Holistic approach Nutr atopic PRO-AMP ®

A specic product line for proactive care, during the AD cycle.

Facial Cream Nutr atopic PRO-AMP ®

Facial

Specific Areas

®

Emollient Cream Nutr atopic PRO-AMP

Rx

Emollient Bath Gel Nutr atopic PRO-AMP Emollient Lotion Nutr atopic PRO-AMP ® ®

Body

Outbreak

Outbreak

Remission

Time

References: 1. Elias PM, Schmuth M. Abnormal skin barrier in the eƟopathogenesis of atopic dermaƟƟs. Curr Opin Allergy Clin Imunol. 2009;9(5):437–446. 2. Berlein-König B, Schäfer T, HussMarp J, et al. Skin surface pH, stratum corneum hydraƟon, transepidermal water loss and skin roughness related to atopic eczema and skin dryness in… Acta Derm Venereol. 2000; 80(3):188–191. 3. Michael J. Cork, et al. Epidermal Barrier DysfuncƟon in Atopic DermaƟƟs. Journal of InvesƟgaƟve Dermatology (2009) 129, 1892–1908; 4. Leyden JJ, Marples RR, Kligman AM. Staphylococcus aureus in the lesions of atopic dermaƟƟs. Br J Dermatol. 1974;90(5):525–530. 5. Marseglia A, Licari A, AgosƟnis F, et al. Efficacy of a rhamnoso�, ceramides and Lisoleucine cream in atopic eczema of the face: a randomized controlled trial. Pediatr Allergy Immunol 2014: 00. 6. An essenƟal amino acid induces epithelial b-defensin expression Pascale Fehlbaum, Meena Rao, Michael Zaslo*, and G. Mark Anderson; PNAS November 7, 2000 vol. 97 no. 23 pag 12723±12728. 7. Rivas-SanƟago InducƟon of b-defensins by l-isoleucine as novel immunotherapy in experimental murine tuberculosis. Clinical and Experimental Immunology ; 2011; 164: 80–89. 8. Defensins: AnƟmicrobial PepƟdes of innate immunity Tomas Ganz. Nature Reviews, Immunology Vol. 3 September 2003 710-720. 9. Lai Y, Gallo RL (2009) AMPed up immunity: how anƟmicrobial pepƟdes have mulƟple roles in immune defense. Trends Immunol 30:131–41. 10. Rhamnoso�� HP InflammaƟon so�ening, polysaccharide, special dammage skin. Solabia studys, France, 2011. Assessment of Rhamnoso�� HP effect on the adhesion of bacteria to the skin; Assessment of the effect of Rhamnoso�� HP on the aƩenuaƟon of a skin inflammaƟon (Data on file). 11. Puviani M, AgosƟnis F, Milani M. Barrier repair therapy for facial atopic eczema with a non-steroidal emollient cream containing rhamnoso�, ceramides and iso-leucine. A six-case report series. Minerva Pediatr 2014;66 Distributor: Glenmark PharmaceuƟcals South Africa (Pty) Ltd, 34 Monte Carlo Crescent, Block A, First Floor, Kyalami Park, Midrand, 1684. T: (011) 564 3900 | F: (011) 564 3939 | www.glenmarkpharma.co.za | ISDINNTP 07/2020